once in a lifetime

idiom

: very rare or very rarely
a once-in-a-lifetime opportunity
This sort of opportunity comes along once in a lifetime.

Examples of once in a lifetime in a Sentence

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However, unlike other risk factors, lipoprotein(a) levels are purely genetic, thus not influenced by lifestyle, and need only be measured once in a lifetime. Mary J. Scourboutakos, The Conversation, 19 Dec. 2025 Yeomans agrees these once in a lifetime storms are occurring more often and closer together. Carol Thompson, CBS News, 19 Dec. 2025 For the newest Opry members, this night is a once in a lifetime opportunity. Gabrielle Chenault, Nashville Tennessean, 29 Nov. 2025 Obviously, singing with Cynthia is always once in a lifetime. Caitlin Huston, HollywoodReporter, 26 Nov. 2025 See All Example Sentences for once in a lifetime

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“Once in a lifetime.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/once%20in%20a%20lifetime. Accessed 24 Dec. 2025.

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